PharmD · North Dakota

Collaborative Drug Therapy Management for Pharmacists in North Dakota

Not unconditionally. North Dakota calls it a Collaborative Practice Agreement.

Practice authorityConditional independence
Written agreementNo agreement required
What North Dakota calls itCollaborative Practice Agreement
Agreement familyCollaborative Practice
Research date2026-09-03 · clauses 2026-09-03

Uniquely tiered: § 43-15-31.6 grants pharmacists real independent prescribing for an enumerated list of conditions/devices with no physician agreement, while broader drug-therapy initiation/modification outside that list requires the written collaborative agreement under § 43-15-31.4 — see the note under Written agreement.

Independent practice requires: prescribing only from the specific statutory list of conditions/devices under N.D. Cent. Code § 43-15-31.6 (lice, cold sores, motion sickness, hypoglycemia, influenza/strep/COVID-19 after a positive point-of-care test, PEP, travel medicine after CE, emergency epinephrine/diphenhydramine, Lyme prophylaxis, certain devices) — this tier needs no physician agreement at all.

What the collaboration must look like

The rules the physician relationship has to follow. Each fact comes from the statute or board rule listed under sources.

Proximity

Not codified

Supervision ratio

Not codified — no cap on file

Chart review

Not codified

Meeting cadence

Not codified

Prescriptive authority

collaborative-agreement tier (drug therapy initiation/modification beyond the independent list): Separate prescribing terms required · no controlled-substance authority

Requires shared access to the patient's medical record and immediate notification of the collaborating physician/APRN whenever the pharmacist initiates or modifies drug therapy (§ 43-15-31.4(5)). No controlled-substance authority found under this tier.

independent statutory list (§ 43-15-31.6): No agreement needed to prescribe · no controlled-substance authority

Limited to the enumerated conditions/devices in § 43-15-31.6; requires a bona fide patient-pharmacist relationship, a maintained assessment protocol, and notifying the patient's PCP within 3 business days. Therapeutic substitution (§ 43-15-31.7) is separately authorized but expressly EXCLUDES Schedule II controlled substances, antidepressants, antipsychotics, chemotherapy agents, biologics, and narrow-therapeutic-index drugs.

Written agreement

Not required

False reflects the § 43-15-31.6 independent-list tier, which needs no agreement. Broader prescriptive practice — initiating/modifying drug therapy outside that enumerated list — requires a written collaborative agreement with a physician or APRN under § 43-15-31.4, executed either individually or via a medical-director/pharmacist-in-charge umbrella agreement covering multiple providers.

Practice ownership (corporate practice of medicine)

Non-licensee ownership permitted

Sources for the supervision rules (4)
  • N.D. Cent. Code § 43-15-31.4 — Limited prescriptive practices under collaborative agreement
  • N.D. Cent. Code § 43-15-31.5 — Drug administration authority
  • N.D. Cent. Code § 43-15-31.6 — Independent statutory prescriptive authority
  • N.D. Cent. Code § 43-15-31.7 — Therapeutic substitution
The document: Collaborative Practice Agreement
When a North Dakota Collaborative Practice Agreement is required, what it contains and who signs: read the Collaborative Practice Agreement page on practiceagreement.com.

What a collaborating physician costs here

Typical monthly cost in North Dakota

$500$600

Estimate for one Pharmacist. Standard-tier state.

About North Dakota's rules

H.B. 1175 (2019, eff. 2020) and a 2022 rule amendment repealed ND's old PA supervision-contract/ratio/countersignature model — PAs are now CONDITIONAL only below 4,000 practice hours or outside a qualifying facility. All four APRN roles (NP, CRNA, CNM, CNS) are FULL independent practice with no collaboration agreement of any kind.

Other clinicians in North Dakota: see the state overview.

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