PharmD · Massachusetts

Collaborative Drug Therapy Management for Pharmacists in Massachusetts

Yes, a written agreement with a physician is required before you manage drug therapy. Massachusetts calls it a Collaborative Practice Agreement.

Practice authoritySupervision required
Written agreementAgreement required
What Massachusetts calls itCollaborative Practice Agreement
Agreement familyCollaborative Practice
Research date2026-09-03 · clauses 2026-09-03

Represents MA's Collaborative Drug Therapy Management (CDTM) tier (247 CMR 16.00), not base pharmacist licensure. CDTM is permanently physician-agreement-dependent with no independence pathway; community-pharmacy CDTM is limited to 9 enumerated chronic conditions and Schedule VI (non-controlled) drugs only.

What the collaboration must look like

The rules the physician relationship has to follow. Each fact comes from the statute or board rule listed under sources.

Proximity

Not codified — left to the agreement

Supervision ratio

Not codified — no cap on file

Chart review

Percentage set by agreement · As needed

No periodic percentage-based chart review is codified. Instead, each prescriptive action taken under the CPA (initiating, modifying, or discontinuing therapy) must be documented and the supervising physician notified within 24 hours (247 CMR 16.03).

Meeting cadence

Not codified — left to the agreement

Prescriptive authority

community-pharmacy CDTM: Covered by the practice agreement · no controlled-substance authority

Limited to 9 enumerated chronic conditions (asthma, COPD, diabetes, hypertension, hyperlipidemia, CHF, HIV/AIDS, osteoporosis, and identified comorbidities); may extend existing therapy up to two additional 30-day periods, and administer vaccines. Schedule II–V controlled substances are explicitly excluded; only Schedule VI (non-controlled) prescribing is authorized (247 CMR 16.03).

hospital/long-term-care/hospice/ambulatory-clinic CDTM (as opposed to community pharmacy): Covered by the practice agreement · no controlled-substance authority

247 CMR 16.02 requires a pharmacist with prescriptive authority under any CDTM setting to maintain controlled-substance registration, which suggests institutional CDTM scope may reach controlled substances more broadly than the community-pharmacy tier; the entry shows the conservative reading.

Written agreement

Required

Practice ownership (corporate practice of medicine)

Non-licensee ownership permitted — No pharmacist-ownership requirement is generally understood to apply to Massachusetts pharmacy registration (M.G.L. c. 112, § 39 et seq.); a licensed pharmacist must retain professional control over dispensing

Materially more permissive than the M.G.L. c. 156A professional-corporation regime governing PA/NP/CRNA/CNM/CNS/RN above, consistent with the pattern seen in every other state on file.

Sources for the supervision rules (1)
The document: Collaborative Practice Agreement
What a Massachusetts Collaborative Practice Agreement must contain, who governs it and who signs: read the Collaborative Practice Agreement page on practiceagreement.com.

What a collaborating physician costs here

Typical monthly cost in Massachusetts

$500$600

Estimate for one Pharmacist. Standard-tier state.

About Massachusetts's rules

Full practice authority (Acts 2020, c. 260, § 36; 244 CMR 4.00) lets NPs, PMHNPs and CNMs practice independently in Massachusetts: CNMs immediately, NPs and PMHNPs after a Board-attested transition (244 CMR 4.07). PAs and CRNAs have no independent-practice pathway. Massachusetts's professional-corporation ownership rules (M.G.L. c. 156A) are notably strict, and APRN and PA entity ownership remains unsettled.

Other clinicians in Massachusetts: see the state overview.

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